Fibroblast Growth Factor 15/19: From Basic Functions to Therapeutic Perspectives
نویسندگان
چکیده
منابع مشابه
The mouse int-2 gene exhibits basic fibroblast growth factor activity in a basic fibroblast growth factor-responsive cell line.
The int-2 protein is related to basic fibroblast growth factor (bFGF) by amino acid sequence homology. To assess its biological activity, we constructed retroviral vectors containing four variants of mouse int-2 complementary DNA under the transcriptional control of the beta-actin promoter and tested their effects on human SW13 adrenal cortical tumor cells. This cell line specifically requires ...
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BACKGROUND Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing whichimproves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects ...
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Restrictions in neuronal fate occur during the transition from a multipotential to a postmitotic cell. This and later steps in neuronal differentiation are determined by extracellular signals. We report that basic fibroblast growth factor is mitogenic for stem cells and is a differentiation factor for calbindin-expressing hippocampal neurons. The neurotrophin NT-3 is a differentiation factor fo...
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ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 2018
ISSN: 0163-769X,1945-7189
DOI: 10.1210/er.2018-00134